Your source for all things hereditary angioedema

Hereditary angioedema (HAE) is a rare disease caused by a deficiency or dysfunction of an important protein found in blood called C1 esterase inhibitor (C1-INH). HAE can cause swelling in certain parts of the body, such as the stomach, hands, and face. The swelling can be painful and, in some cases, life threatening. HAE is genetic, meaning it runs in families.

If you or a family member has HAE, it's important to know that you're not alone; support is available.

Learn more about the cause and types of HAE

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All about connecting

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Your life is bigger than HAE.

All about symptoms

The symptoms of HAE can sometimes be mistaken for other common medical problems, such as allergic reactions or stomach issues. But certain clues can help physicians make the correct diagnosis.

See the signs of HAE

All about managing HAE

Find out more about treatments that can help prevent attacks and ones that can treat attacks as they occur.

Learn about treatments
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For physicians and healthcare professionals

View helpful information on identifying and diagnosing HAE and find useful resources to improve patient care.

HAE signs and symptoms

Explore clinical resources

Your setback can be the setup for your comeback!

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