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Q: What is hereditary angioedema (HAE)?

A: People suffering from HAE have a low level of an important protein in their blood. The protein is called C1-INH (pronounced C1 inhibitor, which is short for C1 esterase inhibitor). C1-INH regulates and "turns off" various reactions in the body. A low level or decreased function of C1-INH is thought to be the major reason for recurrent, often severe or even life-threatening swelling (angioedema) in different parts of the body in people with HAE.

Answered By: Henry Li, MD

Document Published: 12/21/2006 3:56 PM
Last Updated: 12/21/2006 3:56 PM

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