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About HAE

Disease Overview
Hereditary angioedema (HAE) is caused by low levels of functional C1-INH and generates potentially fatal non-pitting edema.

Symptoms of HAE
A variety of symptoms are associated with hereditary angioedema (HAE).

Etiology & Prevalence
Hereditary angioedema (HAE) accounts for only 2% of clinical angioedema cases and affects both sexes, all ethnic groups, etc.

Pathophysiology
In hereditary angioedema (HAE), the low levels of functional Complement-1 Esterase Inhibitor (C1-INH) lead to unregulated activation of the complement, contact, fibrinolytic, and coagulation cascades and the development of angioedema with its associated complications.

Types of HAE
There are various types of hereditary angioedema (HAE).

Glossary
This page contains glossary terms pertaining to hereditary angioedema (HAE).

Last Modified Date: 6/22/2009 3:55 PM